Novel Synthesis of 1,2-Substituted 4-Quinolones
نویسندگان
چکیده
منابع مشابه
Synthesis of phenanthridones using Diels-Alder reactions of 4-substituted 2(1H)-quinolones acting as dienophiles.
Diels-Alder reactions of 2(1H)-quinolones having an electron-withdrawing group at the 4-position with 1,3-butadiene derivatives were carried out to give the phenanthridones richly functionalized under the conditions of atmospheric and high pressure. Furthermore, the reactivities of 4-substituted 2(1H)-quinolones acting as a dienophile were examined using MO calculation.
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A variety of novel 4-[(4'-substituted phenyl)-6-(4"-hydroxyphenyl)-2-substituted imino] pyrimidines were synthesized by reacting 4-(4'-substituted phenyl)-6-(4"-hydroxyphenyl)-2-aminopyrimidines with different substituted aromatic aldehydes, with coumarin and with chloroisatin. The 4-(4'-chlorophenyl)-6-(4"-hydroxyphenyl)-2-aminopyrimidines were synthesized by reacting 3-(4'-substituted phenyl)...
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Heterocyclic compounds are very widely distributed in nature and are essential to life as they play a vital role in the metabolism of living cells. There are a vast number of pharmacologically active heterocyclic compounds of which many are in regular therapeutic usage. Among various heterocyclic compounds, quinoline-based drugs such as quinine, chloroquine, pamaquine and quinacrine are well kn...
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ژورنال
عنوان ژورنال: SynOpen
سال: 2018
ISSN: 2509-9396
DOI: 10.1055/s-0037-1610388